ovarian cancer Essay -- essays research papers

Of all gynecologic malignancies, ovarian crab louse continues to have the highest death rate and is the most difficult to diagnose. In the United States female population, ovarian cancer ranks fifth in absolute mortality among cancer related deaths (13,000/yr). In most reported cases, ovarian cancer, when starting line diagnosed is in stages III or IV in about 60 to 70% of patients which further complicates sermon of the disease (Barber, 3). Early detection in ovarian cancer is hampered by the lack of appropriate tumor markers and clinically, most patients fail to develop authoritative symptoms until they reach advanced stage disease. The characteristics of ovarian cancer have been study in primary tumors and in established ovarian tumor cellphone lines which provide a reproducible source of tumor material. Among the major clinical problems of ovarian cancer, malignant progression, rapid emergence of drug resistance, and associated cross-resistance remain unresolved. ovarian cancer has a high frequency of metastasis yet generally mud localized within the peritoneal cavity. Tumor development has been associated with aberrant, dysfunctional preparation and/or mutation of various genes. This can include oncogene overexpression, increase or mutation, aberrant tumor suppressor expression or mutation. Also, degeneracy of host antitumor immune responses may play a grapheme in the pathogenesis of cancer (Sharp, 77). Ovarian clear cell adenocarcinoma was first described by...